Hormonal decline during perimenopause and menopause is a major, often overlooked driver of systemic symptoms and long-term disease risk. This protocol focuses on supporting detoxification, optimizing hormone metabolism, and preparing the body for effective hormone replacement therapy. Designed for women in perimenopause (starting around age 35) or menopause (average age 51), it provides a foundational approach to reduce endocrine disruptors, improve symptom stability, and support long-term health and resilience.